Norepinephrine release from Locus Ceruleus:a central regulator for the CNS spatio-temporal activation pattern?

Norepinephrine (NE) is synthesized in the Locus Coeruleus (LC) of the brainstem, from where it is released by axonal varicosities throughout the brain via volume transmission. A wealth of data from clinics and from animal models indicates that this catecholamine coordinates the activity of the centr...

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Main Authors: Marco Atzori, Roberto Cuevas-Olguin, Eric Esquivel-Rendon, Francisco Garcia-Oscos, Roberto Carlos Salgado-Delgado, Nadia Saderi, Marcela Miranda-Morales, Mario Treviño Villegas, Juan Carlos Pineda, Humberto Salgado-Burgos
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Synaptic Neuroscience
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Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00025/full