Intermittent peripheral exposure to lipopolysaccharide induces exploratory behavior in mice and regulates brain glial activity in obese mice

Intermittent peripheral exposure to lipopolysaccharide induces exploratory behavior in mice and regulates brain glial activity in obese mice

Abstract Background Consecutive peripheral immune challenges can modulate the responses of brain resident microglia to stimuli. High-fat diet (HFD) intake has been reported to stimulate the activation of astrocytes and microglia in the arcuate nucleus (ARC) of the hypothalamus in obese rodents and h...

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Bibliographic Details
Main Authors: Hui-Ting Huang, Po-See Chen, Yu-Min Kuo, Shun-Fen Tzeng
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Journal of Neuroinflammation
Subjects:
Peripheral inflammation
Obesity
Microglia
Gliosis
Exploration
Online Access:http://link.springer.com/article/10.1186/s12974-020-01837-x

Internet

http://link.springer.com/article/10.1186/s12974-020-01837-x

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