Association between P(16INK4a) promoter methylation and non-small cell lung cancer: a meta-analysis.

BACKGROUND: Aberrant methylation of CpG islands acquired in tumor cells in promoter regions plays an important role in carcinogenesis. Accumulated evidence demonstrates P(16INK4a) gene promoter hypermethylation is involved in non-small cell lung carcinoma (NSCLC), indicating it may be a potential bi...

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Bibliographic Details
Main Authors: Jundong Gu, Yanjun Wen, Siwei Zhu, Feng Hua, Hui Zhao, Hongrui Xu, Jiacong You, Linlin Sun, Weiqiang Wang, Jun Chen, Qinghua Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618325?pdf=render