Programmable Nuclease-Based Integration into Novel Extragenic Genomic Safe Harbor Identified from Korean Population-Based CNV Analysis

Here, we found two genomic safe harbor (GSH) candidates from chromosomes 3 and 8, based on large-scale population-based cohort data from 4,694 Koreans by CNV analysis. Furthermore, estimated genotype of these CNVRs was validated by quantitative real-time PCR, and epidemiological data examined no sig...

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Bibliographic Details
Main Authors: Eun-Seo Lee, Sanghoon Moon, Kwaku Dad Abu-Bonsrah, Yun Kyoung Kim, Mi Yeong Hwang, Young Jin Kim, Seokjoong Kim, Nathaniel S. Hwang, Hyongbum Henry Kim, Bong-Jo Kim
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770519300671