Selective Delivery of a Therapeutic Gene for Treatment of Head and Neck Squamous Cell Carcinoma Using Human Neural Stem Cells

Selective Delivery of a Therapeutic Gene for Treatment of Head and Neck Squamous Cell Carcinoma Using Human Neural Stem Cells

ObjectivesBased on studies of the extensive tropism of neural stem cells (NSCs) toward malignant brain tumor, we hypothesized that NSCs could also target head and neck squamous cell carcinoma (HNSCC) and could be used as a cellular therapeutic delivery system.MethodsTo apply this strategy to the tre...

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Bibliographic Details
Main Authors: Seong Keun Kwon, Seung U Kim, Jae-Jun Song, Chang Gun Cho, Seok-Won Park
Format: Article
Language:English
Published: Korean Society of Otorhinolaryngology-Head and Neck Surgery 2013-09-01
Series:Clinical and Experimental Otorhinolaryngology
Subjects:
Head and neck neoplasms
Neural stem cells
Tropism
Cytosine deaminase
Molecular targeted therapy
Online Access:http://www.e-ceo.org/upload/pdf/ceo-6-176.pdf

Internet

http://www.e-ceo.org/upload/pdf/ceo-6-176.pdf

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