Beyond the IFA: Revisiting the ELISA as a More Sensitive, Objective, and Quantitative Evaluation of Spotted Fever Group <i>Rickettsia</i> Exposure

Beyond the IFA: Revisiting the ELISA as a More Sensitive, Objective, and Quantitative Evaluation of Spotted Fever Group <i>Rickettsia</i> Exposure

Based on limited serological studies, at least 10% of the US population has been exposed to spotted fever group <i>Rickettsia</i> (SFGR) species. The immunofluorescence antibody assay (IFA) has been the gold standard for the serodiagnosis of rickettsial infections such as spotted fever r...

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Bibliographic Details
Main Authors: Navatha Alugubelly, John V. Stokes, Claire E. Cross, Anne-Marie L. Ross, Anna E. Crawford, Gabrielle F. Fiihr, Andrea S. Varela-Stokes
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Pathogens
Subjects:
<i>Rickettsia parkeri</i>
Rickettsia amblyommatis
guinea pig
serology
tick-borne diseases
<i>Amblyomma</i>
Online Access:https://www.mdpi.com/2076-0817/10/2/88

Internet

https://www.mdpi.com/2076-0817/10/2/88

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