The role of the receptor for advanced glycation end-products in a murine model of silicosis.

The role of the receptor for advanced glycation end-products (RAGE) has been shown to differ in two different mouse models of asbestos and bleomycin induced pulmonary fibrosis. RAGE knockout (KO) mice get worse fibrosis when challenged with asbestos, whereas in the bleomycin model they are largely p...

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Bibliographic Details
Main Authors: Lasse Ramsgaard, Judson M Englert, Jacob Tobolewski, Lauren Tomai, Cheryl L Fattman, Adriana S Leme, A Murat Kaynar, Steven D Shapiro, Jan J Enghild, Tim D Oury
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2841632?pdf=render