Involvement of PPARs in Cell Proliferation and Apoptosis in Human Colon Cancer Specimens and in Normal and Cancer Cell Lines

PPAR involvement in cell growth was investigated “in vivo” and “in vitro” and was correlated with cell proliferation and apoptotic death. “In vivo” PPARγ and α were evaluated in colon cancer specimens and adjacent nonneoplastic colonic mucosa. PPARγ increased in most cancer specimens versus mucosa,...

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Bibliographic Details
Main Authors: G. Martinasso, M. Oraldi, A. Trombetta, M. Maggiora, O. Bertetto, R. A. Canuto, G. Muzio
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:PPAR Research
Online Access:http://dx.doi.org/10.1155/2007/93416