TRIM22 inhibits the proliferation of gastric cancer cells through the Smad2 protein

Abstract TRIM22 is involved in tumorigenesis and development, but its mechanism is not clear. In this study, we investigated the expression and biological role of TRIM22 in gastric cancer. We found that TRIM22 mRNA and protein expression was abnormally low in gastric cancer tissues and cells and cor...

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Bibliographic Details
Main Authors: Zhuqing Zhou, Wei Gao, Biao Yuan, Shun Zhang, Kaijing Wang, Tao Du
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00627-5