The effect of growth-mimicking continuous strain on the early stages of skeletal development in micromass culture.

Embryonic skeletogenesis involves proliferation, condensation and subsequent chondrogenic differentiation of mesenchymal precursor cells, and the strains and stresses inherent to these processes have been hypothesized to influence skeletal development. The aim of this study was to determine the effe...

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Bibliographic Details
Main Authors: Darinka D Klumpers, Theo H Smit, David J Mooney
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411057?pdf=render