Identification of novel genes and pathways regulating SREBP transcriptional activity.

<h4>Background</h4>Lipid metabolism in mammals is orchestrated by a family of transcription factors called sterol regulatory element-binding proteins (SREBPs) that control the expression of genes required for the uptake and synthesis of cholesterol, fatty acids, and triglycerides. SREBPs...

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Bibliographic Details
Main Authors: Sandipan Chatterjee, Joseph D Szustakowski, Nirmala R Nanguneri, Craig Mickanin, Mark A Labow, Axel Nohturfft, Kumlesh K Dev, Rajeev Sivasankaran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19381295/pdf/?tool=EBI