In silico and in vivo splicing analysis of <it>MLH1 </it>and <it>MSH2 </it>missense mutations shows exon- and tissue-specific effects
<p>Abstract</p> <p>Background</p> <p>Abnormalities of pre-mRNA splicing are increasingly recognized as an important mechanism through which gene mutations cause disease. However, apart from the mutations in the donor and acceptor sites, the effects on splicing of other...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2006-09-01
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| Series: | BMC Genomics |
| Online Access: | http://www.biomedcentral.com/1471-2164/7/243 |