Reconciling the IPC and Two-Hit Models: Dissecting the Underlying Cellular and Molecular Mechanisms of Two Seemingly Opposing Frameworks

Inflammatory cascades and mechanisms are ubiquitous during host responses to various types of insult. Biological models and interventional strategies have been devised as an effort to better understand and modulate inflammation-driven injuries. Amongst those the two-hit model stands as a plausible a...

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Bibliographic Details
Main Authors: Carlos F. M. Morris, Muhammad Tahir, Samina Arshid, Mariana S. Castro, Wagner Fontes
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2015/697193