The Role of Tissue Oxygen Tension in Dengue Virus Replication

The Role of Tissue Oxygen Tension in Dengue Virus Replication

Low oxygen tension exerts a profound effect on the replication of several DNA and RNA viruses. In vitro propagation of Dengue virus (DENV) has been conventionally studied under atmospheric oxygen levels despite that in vivo, the tissue microenvironment is hypoxic. Here, we compared the efficiency of...

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Bibliographic Details
Main Authors: Efseveia Frakolaki, Panagiota Kaimou, Maria Moraiti, Katerina I. Kalliampakou, Kalliopi Karampetsou, Eleni Dotsika, Panagiotis Liakos, Dido Vassilacopoulou, Penelope Mavromara, Ralf Bartenschlager, Niki Vassilaki
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Cells
Subjects:
hypoxia
dengue virus
hepatocytes
HIF
AKT
metabolic reprogramming
glycolysis
Online Access:https://www.mdpi.com/2073-4409/7/12/241

Internet

https://www.mdpi.com/2073-4409/7/12/241

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