MyD88-adaptor protein acts as a preventive mechanism for memory deficits in a mouse model of Alzheimer's disease

<p>Abstract</p> <p>Background</p> <p>Alzheimer's disease (AD) is an age-related neurodegenerative disorder associated with brain innate immune activation mainly mediated by microglia. These cells are known to be activated in the brain of AD patients and to produce...

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Bibliographic Details
Main Authors: Rivest Serge, Richard Karine L, Michaud Jean-Philippe
Format: Article
Language:English
Published: BMC 2011-01-01
Series:Molecular Neurodegeneration
Online Access:http://www.molecularneurodegeneration.com/content/6/1/5