Unacylated ghrelin suppresses ghrelin-induced neuronal activity in the hypothalamus and brainstem of male rats [corrected].

Ghrelin, the endogenous growth hormone secretagogue, has an important role in metabolic homeostasis. It exists in two major molecular forms: acylated (AG) and unacylated (UAG). Many studies suggest different roles for these two forms of ghrelin in energy balance regulation. In the present study, we...

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Bibliographic Details
Main Authors: Darko M Stevanovic, Aldo Grefhorst, Axel P N Themmen, Vera Popovic, Joan Holstege, Elize Haasdijk, Vladimir Trajkovic, Aart-Jan van der Lely, Patric J D Delhanty
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4031147?pdf=render