Deconstructing the principles of ductal network formation in the pancreas.

The mammalian pancreas is a branched organ that does not exhibit stereotypic branching patterns, similarly to most other glands. Inside branches, it contains a network of ducts that undergo a transition from unconnected microlumen to a mesh of interconnected ducts and finally to a treelike structure...

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Bibliographic Details
Main Authors: Svend Bertel Dahl-Jensen, Siham Yennek, Lydie Flasse, Hjalte List Larsen, Dror Sever, Gopal Karremore, Ivana Novak, Kim Sneppen, Anne Grapin-Botton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-07-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC6080801?pdf=render