Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis

Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis

Abstract Molecular mechanisms underlying breast cancer lymph node metastasis remain unclear. Using single-cell sequencing, we investigated the transcriptome profile of 96,796 single cells from 15 paired samples of primary tumors and axillary lymph nodes. We identified nine cancer cell subclusters in...

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Bibliographic Details
Main Authors: Kun Xu, Runtian Wang, Hui Xie, Longfei Hu, Cong Wang, Jiali Xu, Chengjun Zhu, Yiqiu Liu, Fangyan Gao, Xintong Li, Cenzhu Wang, Jinyi Huang, Wenbin Zhou, Guohua Zhou, Yongqian Shu, Xiaoxiang Guan
Format: Article
Language:English
Published: Nature Publishing Group 2021-10-01
Series:Oncogenesis
Online Access:https://doi.org/10.1038/s41389-021-00355-6

Internet

https://doi.org/10.1038/s41389-021-00355-6

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