RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner
RPGR (retinitis pigmentosa GTPase regulator) is a ciliary protein associated with several forms of inherited retinal degenerative diseases. PDE6D is a ubiquitously expressed prenyl-binding protein and involved in ciliary targeting of prenylated proteins. The current working model for the RPGR functi...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2016-09-01
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Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/5/9/1283 |