RPGR, a prenylated retinal ciliopathy protein, is targeted to cilia in a prenylation- and PDE6D-dependent manner

RPGR (retinitis pigmentosa GTPase regulator) is a ciliary protein associated with several forms of inherited retinal degenerative diseases. PDE6D is a ubiquitously expressed prenyl-binding protein and involved in ciliary targeting of prenylated proteins. The current working model for the RPGR functi...

Full description

Bibliographic Details
Main Authors: Nirmal Dutta, Seongjin Seo
Format: Article
Language:English
Published: The Company of Biologists 2016-09-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/5/9/1283