Methylene Blue Prevents Retinal Damage Caused by Perinatal Asphyxia in the Rat

Methylene Blue Prevents Retinal Damage Caused by Perinatal Asphyxia in the Rat

Perinatal asphyxia (PA) is responsible for a large proportion of neonatal deaths and numerous neurological sequelae, including visual dysfunction and blindness. In PA, the retina is exposed to ischemia/reoxygenation, which results in nitric oxide (NO) overproduction and neurotoxicity. We hypothesize...

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Bibliographic Details
Main Authors: Juan Carlos Fernández, Rafael Peláez, Manuel Rey-Funes, Manuel Soliño, Daniela S. Contartese, Verónica B. Dorfman, Juan José López-Costa, Ignacio M. Larrayoz, César F. Loidl, Alfredo Martínez
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular Neuroscience
Subjects:
angiogenesis
apoptosis
electroretinography
inner retinal thickness
methylene blue
perinatal asphyxia
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2020.00157/full

Internet

https://www.frontiersin.org/article/10.3389/fncel.2020.00157/full

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