Contribution of the R8 substituent to the in vitro antibacterial potency of besifloxacin and comparator ophthalmic fluoroquinolones

Wolfgang Haas, Christine M Sanfilippo, Christine K Hesje, Timothy W Morris Department of Microbiology and Sterilization Sciences, Bausch + Lomb, Inc, Rochester, NY, USA Introduction: Previous work has shown that besifloxacin, an 8-chloro-fluoroquinolone, has more potent activity against gram-positiv...

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Bibliographic Details
Main Authors: Haas W, Sanfilippo CM, Hesje CK, Morris TW
Format: Article
Language:English
Published: Dove Medical Press 2013-05-01
Series:Clinical Ophthalmology
Online Access:http://www.dovepress.com/contribution-of-the-r8-substituent-to-the-in-vitro-antibacterial-poten-a12948