Dendritic macromolecules as nano-scale drug carriers: Phase solubility, in vitro drug release, hemolysis and cytotoxicity study

Potential of nanoscale triazine based dendritic macromolecules G1, G2 and G3 as solubility enhancers of drug was investigated. Effect of pH, concentration and generation of synthesized dendritic macromolecules on solubility of ketoprofen was studied. G3 dendrimer was further exploited as carrier for...

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Bibliographic Details
Main Authors: Pravinkumar M. Patel, Rinkesh Patel, Devang Wadia, Rajni M. Patel
Format: Article
Language:English
Published: Elsevier 2015-07-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087615000288