Investigation of the extremely weak interaction between the Japanese encephalitis virus and CLEC5A using a multivalent-interaction-enhancement sensing electrode
A lectin receptor, CLEC5A, plays an important role in the pathogenic mechanism of dengue virus (DV). The binding affinity between the DV envelope E-protein and CLEC5A is extremely weak and not easily detected using traditional methods, such as ELISA, making the characterization of the binding epitop...
Main Authors: | Yen-Ting Tung, Jian-Jong Liang, Hsiao-Ting Feng, Ruei-Ning Jhang, Shie-Liang Hsieh, Yi-Ling Lin, Gou-Jen Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-10-01
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Series: | Biosensors and Bioelectronics: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590137019300147 |
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