Ovine reference materials and assays for prion genetic testing

<p>Abstract</p> <p>Background</p> <p>Genetic predisposition to scrapie in sheep is associated with several variations in the peptide sequence of the prion protein gene (<it>PRNP</it>). DNA-based tests for scoring <it>PRNP </it>codons are essentia...

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Bibliographic Details
Main Authors: Smith Timothy PL, Freking Brad A, Kalbfleisch Theodore S, Leymaster Kreg A, Heaton Michael P, Clawson Michael L, Laegreid William W
Format: Article
Language:English
Published: BMC 2010-04-01
Series:BMC Veterinary Research
Online Access:http://www.biomedcentral.com/1746-6148/6/23