Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection

Prediction of blood-based biomarkers and subsequent design of bisulfite PCR-LDR-qPCR assay for breast cancer detection

Abstract Background Interrogation of site-specific CpG methylation in circulating tumor DNAs (ctDNAs) has been employed in a number of studies for early detection of breast cancer (BrCa). In many of these studies, the markers were identified based on known biology of BrCa progression, and interrogat...

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Bibliographic Details
Main Authors: Manny D. Bacolod, Jianmin Huang, Sarah F. Giardina, Philip B. Feinberg, Aashiq H. Mirza, Alexander Swistel, Steven A. Soper, Francis Barany
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Cancer
Subjects:
Breast cancer
Methylation
Early detection
Ligase detection reaction
Biomarker
Online Access:https://doi.org/10.1186/s12885-020-6574-4

Internet

https://doi.org/10.1186/s12885-020-6574-4

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