A Label-Free Fluorescent Sensor Based on the Formation of Poly(thymine)-Templated Copper Nanoparticles for the Sensitive and Selective Detection of MicroRNA from Cancer Cells

In this work, a simple and label-free fluorescence “off” to “on” platform was designed for the sensitive and selective detection of microRNA (miRNA) in cancer cells. This method utilized a padlock DNA-based rolling circle amplification (P-RCA) to synthesize fluorescent poly(thymine) (PolyT) which ac...

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Bibliographic Details
Main Authors: Qian Ma, Zhiqiang Gao, Hiranya Dayal, Sam Fong Yau Li
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/8/3/52