LAPTM5–CD40 Crosstalk in Glioblastoma Invasion and Temozolomide Resistance

LAPTM5–CD40 Crosstalk in Glioblastoma Invasion and Temozolomide Resistance

Background: Glioma therapy is challenged by the diffuse and invasive growth of glioma. Lysosomal protein transmembrane 5 (LAPTM5) was identified as an invasion inhibitor by an in vivo screen for invasion-associated genes. The aim of this study was to decipher the function of LAPTM5 in glioblastoma a...

Full description

Bibliographic Details
Main Authors: Anne Berberich, Frederik Bartels, Zili Tang, Maximilian Knoll, Sonja Pusch, Nanina Hucke, Tobias Kessler, Zhen Dong, Benedikt Wiestler, Frank Winkler, Michael Platten, Wolfgang Wick, Amir Abdollahi, Dieter Lemke
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
LAPTM5
CD40
NFκB
temozolomide
glioblastoma
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00747/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.00747/full

Similar Items