Epigenetic regulation of matrix metalloproteinases and their collagen substrates in cancer

Our review covers the recent epigenetic data that are focused on matrix metalloproteinases (MMPs), their inhibitors (tissue inhibitors of MMPs; TIMPs) and collagen substrates. Twenty-four MMPs, four TIMPs and at least 28 collagen types are known in humans. The MMP activity regulates the functionalit...

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Bibliographic Details
Main Authors: Chernov Andrei V., Strongin Alex Y.
Format: Article
Language:English
Published: De Gruyter 2011-06-01
Series:Biomolecular Concepts
Subjects:
mmp
Online Access:https://doi.org/10.1515/bmc.2011.017