Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra

Progressive Parkinsonism by acute dysfunction of excitatory amino acid transporters in the rat substantia nigra

Parkinson's disease (PD) is characterized by the progressive degeneration of substantia nigra (SN) dopamine neurons, involving a multifactorial cascade of pathogenic events. Here we explored the hypothesis that dysfunction of excitatory amino acid transporters (EAATs) might be involved. Acutely...

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Bibliographic Details
Main Authors: Maxime Assous, Laurence Had-Aissouni, Paolo Gubellini, Christophe Melon, Imane Nafia, Pascal Salin, Lydia Kerkerian-Le-Goff, Philippe Kachidian
Format: Article
Language:English
Published: Elsevier 2014-05-01
Series:Neurobiology of Disease
Subjects:
Animal model
Excitotoxicity
Glutamate transporters
Neurodegeneration
Neuroprotection
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114000254

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http://www.sciencedirect.com/science/article/pii/S0969996114000254

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