Role of Sirtuins in Modulating Neurodegeneration of the Enteric Nervous System and Central Nervous System

Neurodegeneration of the central and enteric nervous systems is a common feature of aging and aging-related diseases, and is accelerated in individuals with metabolic dysfunction including obesity and diabetes. The molecular mechanisms of neurodegeneration in both the CNS and ENS are overlapping. Si...

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Bibliographic Details
Main Authors: Pavithra Chandramowlishwaran, Anitha Vijay, Daniel Abraham, Ge Li, Simon Musyoka Mwangi, Shanthi Srinivasan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.614331/full