H3K9me3 is required for inheritance of small RNAs that target a unique subset of newly evolved genes

H3K9me3 is required for inheritance of small RNAs that target a unique subset of newly evolved genes

In Caenorhabditis elegans, RNA interference (RNAi) responses can transmit across generations via small RNAs. RNAi inheritance is associated with Histone-3-Lysine-9 tri-methylation (H3K9me3) of the targeted genes. In other organisms, maintenance of silencing requires a feed-forward loop between H3K9m...

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Bibliographic Details
Main Authors: Itamar Lev, Hila Gingold, Oded Rechavi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-03-01
Series:eLife
Subjects:
epigenetics
small RNA
histone methylation
RNAi
H3K9
transgenerational
Online Access:https://elifesciences.org/articles/40448

Internet

https://elifesciences.org/articles/40448

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