New candidate biomarkers in the female genital tract to evaluate microbicide toxicity.

Vaginal microbicides hold great promise for the prevention of viral diseases like HIV, but the failure of several microbicide candidates in clinical trials has raised important questions regarding the parameters to be evaluated to determine in vivo efficacy in humans. Clinical trials of the candidat...

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Bibliographic Details
Main Authors: Scott Fields, Benben Song, Bareza Rasoul, Julie Fong, Melissa G Works, Kenneth Shew, Ying Yiu, Jon Mirsalis, Annalisa D'Andrea
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4205019?pdf=render