Synthesis, QSAR and Molecular Dynamics Simulation of Amidino-substituted Benzimidazoles as Dipeptidyl Peptidase III Inhibitors

Synthesis, QSAR and Molecular Dynamics Simulation of Amidino-substituted Benzimidazoles as Dipeptidyl Peptidase III Inhibitors

A molecular modeling study is performed on series of benzimidazol-based inhibitors of human dipeptidyl peptidase III (DPP III). An eight novel compounds were synthesized in excellent yields using green chemistry approach. This study is aimed to elucidate the structural features of benzimidazole deri...

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Bibliographic Details
Main Authors: Vesna Rastija, Dejan Agić, Sanja Tomić, Sonja Nikolić, Marijana Hranjec, Grace Karminski-Zamola, Marija Abramić
Format: Article
Language:English
Published: Slovenian Chemical Society 2015-11-01
Series:Acta Chimica Slovenica
Subjects:
molecular modeling
dipeptidyl peptidasese III
benzimidazole derivatives
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/1605

Internet

https://journals.matheo.si/index.php/ACSi/article/view/1605

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