Age-related changes in dentate gyrus cell numbers, neurogenesis, and associations with cognitive impairments in the rhesus monkey

The generation of new neurons in the adult mammalian brain is well established for the hippocampal dentate gyrus. However, the role of neurogenesis in hippocampal function and cognition, how it changes in aging, and the mechanisms underlying this are yet to be elucidated in the monkey brain. To ad...

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Bibliographic Details
Main Authors: Laura Benjamin Ngwenya, Nadine C Heyworth, Yamin eShwe, Tara eMoore, Douglas L Rosene
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-07-01
Series:Frontiers in Systems Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsys.2015.00102/full