Lung transcriptional unresponsiveness and loss of early influenza virus control in infected neonates is prevented by intranasal Lactobacillus rhamnosus GG.

Respiratory viral infections contribute substantially to global infant losses and disproportionately affect preterm neonates. Using our previously established neonatal murine model of influenza infection, we demonstrate that three-day old mice are exceptionally sensitive to influenza virus infection...

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Bibliographic Details
Main Authors: Ogan K Kumova, Adam J Fike, Jillian L Thayer, Linda T Nguyen, Joshua Chang Mell, Judy Pascasio, Christopher Stairiker, Leticia G Leon, Peter D Katsikis, Alison J Carey
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008072