Lipopolysaccharide Downregulates CD163 Expression to Inhibit PRRSV Infection via TLR4-NF-κB Pathway

Lipopolysaccharide Downregulates CD163 Expression to Inhibit PRRSV Infection via TLR4-NF-κB Pathway

Porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized to induce proinflammatory cytokine production and modulate the host interferon (IFN) system. Proinflammatory cytokines and type I IFNs contribute to the prevention of viral infection. Lipopolysaccharide (LPS), a specific...

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Bibliographic Details
Main Authors: Zhenbang Zhu, Hui Zhang, Xiaoxiao Zhang, Sheng He, Wenjuan Dong, Xiaoying Wang, Yaosheng Chen, Xiaohong Liu, Chunhe Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
PRRSV
lipopolysaccharide
proinflammatory response
ADAM17
CD163
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00501/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00501/full

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