Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization

Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization

Abstract Background Psoriasis impacts 1–3% of the world’s population and is characterized by hyper-proliferation of keratinocytes and increased inflammation. At the molecular level, psoriasis is commonly driven by a Th17 response, which serves as a major therapeutic target. Microbiome perturbations...

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Bibliographic Details
Main Authors: Hsin-Wen Chang, Di Yan, Rasnik Singh, Jared Liu, Xueyan Lu, Derya Ucmak, Kristina Lee, Ladan Afifi, Douglas Fadrosh, John Leech, Kimberly S. Vasquez, Margaret M. Lowe, Michael D. Rosenblum, Tiffany C. Scharschmidt, Susan V. Lynch, Wilson Liao
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Microbiome
Online Access:http://link.springer.com/article/10.1186/s40168-018-0533-1

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http://link.springer.com/article/10.1186/s40168-018-0533-1

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