Spinal muscular atrophy: Factors that modulate motor neurone vulnerability

Spinal muscular atrophy: Factors that modulate motor neurone vulnerability

Spinal muscular atrophy (SMA), a leading genetic cause of infant death, is a neurodegenerative disease characterised by the selective loss of particular groups of motor neurones in the anterior horn of the spinal cord with concomitant muscle weakness. To date, no effective treatment is available, ho...

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Bibliographic Details
Main Authors: Wen-Yo Tu, Julie E. Simpson, J. Robin Highley, Paul R. Heath
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Neurobiology of Disease
Subjects:
Selective vulnerability
SMA
SMN
Disease modifier
Motor neurone disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117300293

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http://www.sciencedirect.com/science/article/pii/S0969996117300293

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