Development and validation of HPLC and CE methods for simultaneous determination of amlodipine and atorvastatin in the presence of their acidic degradation products in tablets

Two methods were developed for separation and quantitation of amlodipine (AML) and atorvastatin (ATV) in the presence of their acidic degradation products. The first method was a simple isocratic RP-HPLC method while the second was capillary electrophoresis (CE). Degradation products were obtained b...

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Bibliographic Details
Main Authors: Hassan Said A., Elzanfaly Eman S., El-Zeany Salem Badr A., Salem Maissa Y.
Format: Article
Language:English
Published: Sciendo 2016-12-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.1515/acph-2016-0040