MIF Plays a Key Role in Regulating Tissue-Specific Chondro-Osteogenic Differentiation Fate of Human Cartilage Endplate Stem Cells under Hypoxia

Degenerative cartilage endplate (CEP) shows decreased chondrification and increased ossification. Cartilage endplate stem cells (CESCs), with the capacity for chondro-osteogenic differentiation, are responsible for CEP restoration. CEP is avascular and hypoxic, while the physiological hypoxia is dis...

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Bibliographic Details
Main Authors: Yuan Yao, Qiyue Deng, Weilin Song, Huiyu Zhang, Yuanjing Li, Yang Yang, Xin Fan, Minghan Liu, Jin Shang, Chao Sun, Yu Tang, Xiangting Jin, Huan Liu, Bo Huang, Yue Zhou
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671116301278