Ex vivo isolated human vessel perfusion system for the design and assessment of nanomedicines targeted to the endothelium

Abstract Endothelial cells play a central role in the process of inflammation. Their biologic relevance, as well as their accessibility to IV injected therapeutics, make them a strong candidate for treatment with molecularly‐targeted nanomedicines. Typically, the properties of targeted nanomedicines...

Full description

Bibliographic Details
Main Authors: Taras Lysyy, Laura G. Bracaglia, Lingfeng Qin, Claire Albert, Jordan S. Pober, George Tellides, W. Mark Saltzman, Gregory T. Tietjen
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Bioengineering & Translational Medicine
Subjects:
Online Access:https://doi.org/10.1002/btm2.10154