Polymorphisms of Pro-Inflammatory IL-6 and IL-1β Cytokines in Ascending Aortic Aneurysms as Genetic Modifiers and Predictive and Prognostic Biomarkers

Polymorphisms of Pro-Inflammatory IL-6 and IL-1β Cytokines in Ascending Aortic Aneurysms as Genetic Modifiers and Predictive and Prognostic Biomarkers

Background: Previous studies have demonstrated that polymorphisms involved in immune genes can affect the risk, pathogenesis, and outcome of thoracic ascending aortic aneurysms (TAAA). Here, we explored the potential associations of five functional promoter polymorphisms in <i>interleukin-6<...

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Bibliographic Details
Main Authors: Letizia Scola, Rosa Maria Giarratana, Vincenzo Marinello, Valeria Cancila, Calogera Pisano, Giovanni Ruvolo, Giacomo Frati, Domenico Lio, Carmela Rita Balistreri
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomolecules
Subjects:
thoracic ascending aortic aneurysms
proinflammatory cytokines
rs1800795
rs16944
telomere length
MMP9
Online Access:https://www.mdpi.com/2218-273X/11/7/943

Internet

https://www.mdpi.com/2218-273X/11/7/943

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