Spatial memory deficits in a mouse model of late-onset Alzheimer’s disease are caused by zinc supplementation and correlate with amyloid-beta levels
Much of the research in Alzheimer’s disease (AD) that uses mouse models focuses on the early-onset form of the disease, which accounts for less than 5% of cases. In contrast, this study used a late-onset AD model to examine the interaction between increased dietary zinc (Zn) and the apolipoprotein E...
Main Authors: | Jane Margaret Flinn, Parviz Lorenzo Bozzelli, Paul Anthony Adlard, Angela M Railey |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2014-10-01
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Series: | Frontiers in Aging Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnagi.2014.00174/full |
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