Apical CFTR expression in human nasal epithelium correlates with lung disease in cystic fibrosis.

INTRODUCTION: Although most individuals with cystic fibrosis (CF) develop progressive obstructive lung disease, disease severity is highly variable, even for individuals with similar CFTR mutations. Measurements of chloride transport as expression of CFTR function in nasal epithelial cells correlate...

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Bibliographic Details
Main Authors: Marit Arianne van Meegen, Suzanne Willemina Julia Terheggen-Lagro, Kirsten Judith Koymans, Cornelis Korstiaan van der Ent, Jeffrey Matthijn Beekman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3590182?pdf=render