High quality protein sequence alignment by combining structural profile prediction and profile alignment using SABER-TOOTH

<p>Abstract</p> <p>Background</p> <p>Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become unreliable as they approach the so-called 'twilight zone...

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Bibliographic Details
Main Authors: Bastolla Ugo, Minning Jonas, Teichert Florian, Porto Markus
Format: Article
Language:English
Published: BMC 2010-05-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/251