Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study

Linear Energy Transfer Incorporated Spot-Scanning Proton Arc Therapy Optimization: A Feasibility Study

PurposeTo integrate dose-averaged linear energy transfer (LETd) into spot-scanning proton arc therapy (SPArc) optimization and to explore its feasibility and potential clinical benefits.MethodsAn open-source proton planning platform (OpenREGGUI) has been modified to incorporate LETd into optimizatio...

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Bibliographic Details
Main Authors: Xiaoqiang Li, Xuanfeng Ding, Weili Zheng, Gang Liu, Guillaume Janssens, Kevin Souris, Ana M. Barragán-Montero, Di Yan, Craig Stevens, Peyman Kabolizadeh
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
proton therapy
arc therapy
linear energy transfer
plan optimization
spot scanning
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.698537/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.698537/full

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