FURIN and placental syncytialisation: a cautionary tale

Abstract FURIN is a pro-protein convertase previously shown to be important for placental syncytialisation (Zhou et al. [1]), a process of cell fusion whereby placental cytotrophoblast cells fuse to form a multinucleated syncytium. This finding has been broadly accepted however, we have evidence sug...

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Bibliographic Details
Main Authors: Saije K. Morosin, Sarah J. Delforce, Celine Corbisier de Meaultsart, Eugenie R. Lumbers, Kirsty G. Pringle
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03898-z