FA2H is responsible for the formation of 2-hydroxy galactolipids in peripheral nervous system myelins⃞

Myelin in the mammalian nervous system has a high concentration of galactolipids [galactosylceramide (GalCer) and sulfatide] with 2-hydroxy fatty acids. We recently reported that fatty acid 2-hydroxylase (FA2H), encoded by the FA2H gene, is the major fatty acid 2-hydroxylase in the mouse brain. In t...

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Bibliographic Details
Main Authors: Eduardo N. Maldonado, Nathan L. Alderson, Paula V. Monje, Patrick M. Wood, Hiroko Hama
Format: Article
Language:English
Published: Elsevier 2008-01-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520428901