Reawakening retrocyclins: ancestral human defensins active against HIV-1.

Reawakening retrocyclins: ancestral human defensins active against HIV-1.

Human alpha and beta defensins contribute substantially to innate immune defenses against microbial and viral infections. Certain nonhuman primates also produce theta-defensins-18 residue cyclic peptides that act as HIV-1 entry inhibitors. Multiple human theta-defensin genes exist, but they harbor a...

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Bibliographic Details
Main Authors: Nitya Venkataraman, Amy L Cole, Piotr Ruchala, Alan J Waring, Robert I Lehrer, Olga Stuchlik, Jan Pohl, Alexander M Cole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19402752/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19402752/?tool=EBI

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