Reprogramming, oscillations and transdifferentiation in epigenetic landscapes

Abstract Waddington’s epigenetic landscape provides a phenomenological understanding of the cell differentiation pathways from the pluripotent to mature lineage-committed cell lines. In light of recent successes in the reverse programming process there has been significant interest in quantifying th...

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Bibliographic Details
Main Authors: Bivash Kaity, Ratan Sarkar, Buddhapriya Chakrabarti, Mithun K. Mitra
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-25556-9